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Sylvie CORNELIE

Sylvie CORNELIE

ENVT

Sommaire

Résumé

Sylvie Cornélie was trained as an immunologist (PhD at the Pasteur Institute of Lille, France – DNA vaccine) and then became interested in the interface between humans and the mosquito vector. She studied the immune response of humans against saliva in the context of malaria in Senegal in order to define a marker of exposure to the bite of this mosquito. She then strengthened her skills in medical entomology and focused on the impact of resistance on the salivary content of mosquito vectors. Finally, Sylvie worked for 6 years on the molecular characterization of resistance mechanisms in mosquitoes, more particularly in cuticular resistance mechanisms in Anopheles gambiae. She currently holds an engineering position, and she is developing molecular tools (ddPCR and qPCR, expression) for monitoring insecticide resistance in natural populations of Anopheles in Africa and methodologies to elucidate resistance mechanisms. She intervened in many technology transfers, especially in Africa, in order to train partners to molecular biology tools for the monitoring and the characterization of insecticide resistance.

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